{"id":2407,"date":"2023-03-09T15:32:07","date_gmt":"2023-03-09T07:32:07","guid":{"rendered":"https:\/\/www.xiaoniangyucattery.com\/?p=2407"},"modified":"2023-10-26T16:35:05","modified_gmt":"2023-10-26T08:35:05","slug":"%e5%85%b3%e4%ba%8e%e7%bc%85%e5%9b%a0%e7%8c%ab%e7%9a%84hcm%ef%bc%88%e8%82%a5%e5%8e%9a%e5%9e%8b%e5%bf%83%e8%82%8c%e7%97%85%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.xiaoniangyucattery.com\/?p=2407","title":{"rendered":"\u5173\u4e8e\u7f05\u56e0\u732b\u7684HCM\uff08\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff09"},"content":{"rendered":"

\u00a0\u00a0 HCM\uff08Hypertrophic Cardiomyopathy\uff09\u5373\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff0c\u662f\u5bb6\u732b\u4e2d\u6700\u5e38\u89c1\u7684\u5fc3\u810f\u75c5\uff0c\u5176\u7279\u5f81\u662f\u60a3\u732b\u7684\u5de6\u5fc3\u5ba4\u7684\u808c\u8089\u5f02\u5e38\u589e\u5927\u548c\u589e\u539a\uff0c\u5bfc\u81f4\u5de6\u5fc3\u5ba4\u8154\u4f53\u7f29\u5c0f\uff0c\u4ece\u800c\u5f15\u8d77\u6cf5\u8840\u80fd\u529b\u4e0d\u8db3\uff0c\u7ee7\u800c\u5f15\u53d1\u5de6\u5fc3\u623f\u6269\u5f20\u3002\u5176\u75c7\u72b6\u4e3b\u8981\u8868\u73b0\u4e3a\u5145\u8840\u6027\u5fc3\u529b\u8870\u7aed\u3001\u80ba\u6c34\u80bf\u53ca\u7531\u52a8\u8109\u8840\u6813\u5bfc\u81f4\u7684\u540e\u80a2\u808c\u8089\u75c9\u631b\u3001\u540e\u80a2\u7f3a\u8840\u3001\u762b\u75ea\u6216\u5fc3\u6e90\u6027\u731d\u6b7b\u3002\u591a\u53d1\u4e8e\u732b\u4e2d\u5e74\u65f6\u671f\uff0c\u4f46\u6240\u6709\u5e74\u9f84\u6bb5\u5747\u6709\u53ef\u80fd\u53d1\u75c5\uff0c\u96c4\u6027\u53d1\u75c5\u7387\u8981\u9ad8\u4e8e\u96cc\u6027\u3002<\/span><\/h3>\n

\"webwxgetmsgirdtmg\"<\/span><\/h3>\n

\u00a0\u00a0\u00a0HCM\u5728\u7f05\u56e0\u732b\u4e2d\u6709\u591a\u4e25\u91cd\uff1f<\/span><\/h2>\n

\u00a0\u00a0\u00a0\u7814\u7a76\u8868\u660e\u5927\u7ea615%\u7684\u5bb6\u732b\u60a3\u6709HCM\uff0c\u5176\u4e2d\u7f05\u56e0\u732b\u3001\u5e03\u5076\u732b\u662f\u9ad8\u53d1\u54c1\u79cd\uff0c2014\u5e74\u4e00\u9879\u9488\u5bf9\u82f1\u56fd\u56fd\u51852018\u53ea\u5e03\u5076\u732b\u548c742\u53ea\u7f05\u56e0\u732b\u60a3\u75c5\u7387\u7684\u7814\u7a76\u6587\u732e\u663e\u793a\uff0cA31P\u7a81\u53d8\u5728\u6837\u672c\u7f05\u56e0\u732b\u4e2d\u7684\u6d41\u884c\u7387\u662f39.4%\uff1bR820W\u7a81\u53d8\u5728\u6837\u672c\u5e03\u5076\u732b\u4e2d\u7684\u6d41\u884c\u7387\u4e3a27%\u3002[1] \u5728\u8bb8\u591a\u5bf9\u7f05\u56e0\u732bHCM\u7684\u7814\u7a76\u4e2d\u53d1\u73b0\uff0c\u516c\u732b\u4f3c\u4e4e\u6bd4\u6bcd\u732b\u6709\u7740\u66f4\u9ad8\u7684\u60a3\u75c5\u7387\u548c\u75c5\u91cd\u7387\u3002<\/span><\/h3>\n

\u00a0\u00a0\u00a0\u57fa\u56e0\u68c0\u6d4b\u624b\u6bb5\u7684\u53d1\u73b0<\/span><\/h2>\n

\u00a0 \u00a0 HCM\u540c\u6837\u53ef\u80fd\u53d1\u751f\u5728\u4eba\u7c7b\u8eab\u4e0a\uff0c\u4e34\u5e8a\u7814\u7a76\u8868\u660e\u5927\u7ea655%\u7684\u4eba\u7c7b\u75c5\u4f8b\u5b58\u5728\u5bb6\u65cf\u9057\u4f20\u503e\u5411\uff0c\u5728\u732b\u4e2d\uff0c60%\u4ee5\u4e0a\u7684\u60a3\u732b\u88ab\u53d1\u73b0\u5bb6\u65cf\u9057\u4f20\u503e\u5411\u3002\u4eba\u7c7bHCM\u6700\u5e38\u89c1\u7684\u539f\u56e0\u662f\u7f16\u7801\u6784\u6210\u5fc3\u808c\u808c\u8282\u7684\u86cb\u767d\u8d28\u6216\u4e0e\u808c\u8282\u529f\u80fd\u5bc6\u5207\u76f8\u5173\u7684\u86cb\u767d\u8d28\u7684\u57fa\u56e0\u7a81\u53d8\uff0c\u5176\u4e2d\u5927\u90e8\u5206\u5b58\u5728\u4e8e MYH7 \u548c MYBPC3 \u57fa\u56e0\u4e2d\u30022005\u5e74Kathryn M.Meurs\u7b49\u4eba\u5728\u5f53\u65f6\u5bf9\u4eba\u7c7bHCM\u9057\u4f20\u673a\u5236\u7814\u7a76\u6210\u679c\u7684\u57fa\u7840\u4e0a\uff0c\u901a\u8fc7\u5bf9\u7f05\u56e0\u732b\u7684MYBPC3\u57fa\u56e0\u8fdb\u884c\u6d4b\u5e8f\uff0c\u53d1\u73b0\u4e86\u4e00\u4e2a\u4f1a\u5bfc\u81f4\u7f05\u56e0\u732bHCM\u7684A31P\u7a81\u53d8\uff0c\u8fd9\u662f\u5bf9\u732b\u79d1\u52a8\u7269HCM\u9057\u4f20\u539f\u56e0\u7684\u9996\u6b21\u53d1\u73b0\uff0c\u4e5f\u662f\u5728\u975e\u4eba\u7c7b\u7269\u79cd\u4e2d\u7684\u7b2c\u4e00\u6b21\u53d1\u73b0\u3002\u4e24\u5e74\u540e\uff0c\u79d1\u7814\u4eba\u5458\u5728\u5e03\u5076\u732b\u8eab\u4e0a\u53d1\u73b0\u4e86MYBPC3\u57fa\u56e0\u7684\u7b2c\u4e8c\u4e2a\u7a81\u53d8R820W\u3002\u5728\u4e24\u79cd\u81f4\u75c5\u57fa\u56e0\u7a81\u53d8\u88ab\u53d1\u73b0\u540e\uff0c\u79d1\u7814\u4eba\u5458\u5e76\u672a\u505c\u6b62\u52aa\u529b\uff0c\u5bf9\u540c\u6837\u6613\u60a3HCM\u7684\u65af\u82ac\u514b\u65af\u65e0\u6bdb\u732b\u3001\u632a\u5a01\u68ee\u6797\u732b\u3001\u897f\u4f2f\u5229\u4e9a\u68ee\u6797\u732b\u3001\u82f1\u56fd\u77ed\u6bdb\u732b\u7b49\u8fdb\u884c\u4e86\u591a\u4e2a\u4e0e\u5fc3\u808c\u76f8\u5173\u7684\u57fa\u56e0\u7f16\u7801\u6d4b\u5e8f\uff0c\u5e76\u4e14\u68c0\u67e5\u4e86\u4e0eHCM\u76f8\u5173\u7684\u5e8f\u5217\u53d8\u5f02\uff0c\u4f46\u8fdb\u5c55\u7f13\u6162\u3002[2]<\/span><\/h3>\n

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\"2007416232\"<\/span><\/h3>\n

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\u00a0\u00a0\u00a0\u56e0\u6b64\uff0c\u7e41\u80b2\u4eba\u5bf9\u79cd\u732b\u8fdb\u884c\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u57fa\u56e0\u68c0\u6d4b\u5341\u5206\u5fc5\u8981\uff01\u56e0\u4e3a\u901a\u8fc7\u5bf9\u5df2\u77e5\u81f4\u75c5\u57fa\u56e0\u7684\u68c0\u6d4b\u53ef\u4ee5\u5728\u6781\u5927\u7a0b\u5ea6\u4e0a\u7b5b\u9009\u51fa\u643a\u5e26\u81f4\u75c5\u57fa\u56e0\u7684\u732b\u5e76\u53ca\u65f6\u5254\u9664\u51fa\u7e41\u80b2\u8ba1\u5212\u3002\u4f46\u662f\u57fa\u56e0\u68c0\u6d4b\u4e0d\u662f\u514d\u6b7b\u91d1\u724c\uff0c\u56e0\u4e3a\u5373\u4f7f\u57fa\u56e0\u68c0\u6d4b\u7ed3\u679cN\/N\u7684\u732b\u4ecd\u6709\u53ef\u80fd\u60a3HCM\uff0c\u5e76\u5f88\u53ef\u80fd\u9057\u4f20\u7ed9\u540e\u4ee3\uff01<\/span><\/h3>\n

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\u5148\u4e0d\u8981\u614c\uff0c\u9996\u5148HCM\u7a0b\u5ea6\u6709\u8f7b\u91cd\u5206\u671f\uff0c\u5305\u62ec\uff1a<\/span><\/h3>\n

A\u671f-\u6613\u60a3\u5fc3\u808c\u75c5\u4f46\u6ca1\u6709\u5fc3\u808c\u75be\u75c5\u8868\u5f81\u3002<\/span><\/h3>\n

B1\u671f\uff1a\u53d1\u751f\u5145\u8840\u6027\u5fc3\u529b\u8870\u7aed\uff08CHF\uff09\u6216\u52a8\u8109\u8840\u6813\u6813\u585e\uff08ATE\uff09\u98ce\u9669\u8f83\u4f4e\uff08\u5de6\u623f\u6ca1\u6709\u6269\u5f20\u6216\u8f7b\u5ea6\u6269\u5f20\uff09\uff1b<\/span><\/h3>\n

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D\u671f\uff1a\u51fa\u73b0CHF\u4e14\u6cbb\u7597\u56f0\u96be\u6216\u65e0\u6548\u3002<\/span><\/h3>\n

\u00a0 \u00a0 \u5982\u679c\u5fc3\u8d85\u68c0\u6d4b\u53d1\u73b0\u732b\u732b\u5de6\u5fc3\u5ba4\u58c1\u589e\u539a\uff08\u5927\u4e8e\u7b49\u4e8e6mm\uff09\uff0c\u9075\u7167\u533b\u5631\u53ca\u65f6\u590d\u67e5\u589e\u539a\u60c5\u51b5\u4ee5\u53ca\u5de6\u5fc3\u623f\u7684\u6269\u5f20\u60c5\u51b5\uff0cHCM\u7684\u4e25\u91cd\u7a0b\u5ea6\u4e0e\u5de6\u5fc3\u623f\u5927\u5c0f\uff08LA\/Ao\uff09\u5bc6\u5207\u76f8\u5173\u3002\u5f88\u591a\u60a3\u6709HCM\u7684\u732b\u4e00\u8f88\u5b50\u90fd\u6ca1\u6709\u53d1\u75c5\uff0c\u5c3d\u7ba1\u76ee\u524d\u6ca1\u6709\u836f\u7269\u80fd\u591f\u5f7b\u5e95\u6cbb\u6108\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff0c\u4f46\u53ea\u8981\u505a\u5230\u65e9\u53d1\u73b0\u65e9\u6cbb\u7597\uff0c\u5c31\u80fd\u5728\u6700\u5927\u7a0b\u5ea6\u4e0a\u5ef6\u957f\u60a3\u732b\u7684\u751f\u547d\u3002<\/span><\/h3>\n

\u00a0 \u00a0 \u4f5c\u8005\uff1a\u5c0f\u5a18\u9c7c\u7f05\u56e0\u732b\u820d<\/span><\/h3>\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n

    \n
  1. \n

    Prevalence and demographics of the MYBPC3-mutations in ragdolls and Maine coons in the British Isles<\/span><\/h3>\n

    D Casamian-Sorrosal et al. J Small Anim Pract. 2014 May.<\/span><\/h3>\n<\/li>\n
  2. \n

    TheFeline\u00a0Cardiomyopathies:Hypertrophic cardiomyopathy<\/span><\/h3>\n

    Mark D Kittleson and Etienne C\u00f4t\u00e9<\/span><\/h3>\n<\/li>\n<\/ol>\n

    \u00a0 \u00a0 \u00a03.A feline orthologue of the human MYH7 c.5647G>A (p.(Glu1883Lys)) variant causes hypertrophic cardiomyopathy in a Domestic Shorthair cat<\/span>
    \n\u00a0 \u00a0 \u00a0 \u00a0 Tom Schipper et al. Eur J Hum Genet. 2019 Nov.<\/span><\/h3>\n

    \u00a0 \u00a0 \u00a04.A Novel Homozygous Intronic Variant in TNNT2 Associates With Feline Cardiomyopathy James W. McNamara,1,\u2020 Maggie Schuckman,2 Richard C. Becker,1 and Sakthivel Sadayappan1,*<\/span><\/h3>\n

    <\/h3>\n

    <\/h3>\n","protected":false},"excerpt":{"rendered":"

    \u00a0\u00a0 HCM\uff08Hypertrophic Cardiomyopathy\uff09\u5373\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff0c\u662f\u5bb6\u732b\u4e2d\u6700\u5e38\u89c1\u7684\u5fc3\u810f\u75c5\uff0c …<\/p>\n

    \u5173\u4e8e\u7f05\u56e0\u732b\u7684HCM\uff08\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff09<\/span> \u67e5\u770b\u5168\u6587 »<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"categories":[1],"tags":[8],"class_list":["post-2407","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-hcm"],"_links":{"self":[{"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/posts\/2407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2407"}],"version-history":[{"count":3,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/posts\/2407\/revisions"}],"predecessor-version":[{"id":3185,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=\/wp\/v2\/posts\/2407\/revisions\/3185"}],"wp:attachment":[{"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xiaoniangyucattery.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}